myosin i การใช้

• This myosin is also found in the ciliated protozoan " Tetrahymena thermaphila ".
• Myosin is shaped like a long shaft with a rounded end pointed out towards the surface.
• The muscle will remain in this relaxed position until myosin is phosphorylated by MLC kinase and undergoes a conformational change.
• Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains.
• Myosin is the molecular motor of muscle contraction : When it receives a particular chemical signal, it tugs on actin.
• The power stroke occurs at the release of phosphate from the myosin molecule after the ATP hydrolysis while myosin is tightly bound to actin.
• And only after the myosin is allowed to act do the heart cells actually start getting shorter, which of course takes some time.
• The regulatory domain of scallop myosin is a three-chain protein complex that switches on this motor in response to Ca 2 + binding.
• In deformation, one end of myosin is bound to the plasma membrane, while the other end " walks " toward the plus end of the actin filament.
• The ratio of actin to myosin is between 2 : 1 and 10 : 1 in smooth muscle, compared to ~ 6 : 1 in skeletal muscle and 4 : 1 in cardiac muscle.
• The 20-kDa light chain from smooth muscle myosin is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors, but more slowly.
• Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP . Myosin is a hexameric protein composed of a pair of myosin heavy chains ( MYH ) and two pairs of nonidentical light chains.
• Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP . Myosin is a hexameric protein composed of a pair of myosin heavy chains ( MYH ) and two pairs of nonidentical light chains.
• Phosphorylated myosin is able to form crossbridges with actin thin filaments, and the smooth muscle fiber ( i . e ., cell ) contracts via the sliding filament mechanism . ( See reference for an illustration of the signaling cascade involving L-type calcium channels in smooth muscle ).